Isorhamnetin Alleviates Mitochondrial Injury in Severe Acute Pancreatitis via Modulation of KDM5B/HtrA2 Signaling Pathway

Isorhamnetin Alleviates Mitochondrial Injury in Severe Acute Pancreatitis via Modulation of KDM5B/HtrA2 Signaling Pathway

Severe acute pancreatitis (SAP), a widespread inflammatory condition impacting the abdomen with a high mortality rate, poses challenges due to its unclear pathogenesis and the absence of effective treatment options. Isorhamnetin (ISO), a naturally occurring flavonoid, demonstrates robust antioxidant...

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Bibliographic Details
Main Authors: Xiaojuan Li, Tao Wang, Qilong Zhou, Fan Li, Ting Liu, Kun Zhang, Ao Wen, Lijuan Feng, Xiaoling Shu, Simin Tian, Yijiang Liu, Yu Gao, Qing Xia, Guang Xin, Wen Huang
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
severe acute pancreatitis
isorhamnetin
mitochondrial dysfunction
HtrA2
KDM5B
Online Access:https://www.mdpi.com/1422-0067/25/7/3784

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https://www.mdpi.com/1422-0067/25/7/3784

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