MS approaches to select peptides with post-translational modifications from amphibian defense secretions prior to full sequence elucidation

MS approaches to select peptides with post-translational modifications from amphibian defense secretions prior to full sequence elucidation

Peptide families are characterized by structural motifs, which often comprise specific post-translational modifications (PTMs) required for biological activity. In conventional bioactivity-based peptidomics studies natural peptide mixtures are chromatographically separated and the bioactive fraction...

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Bibliographic Details
Main Authors: Martijn Pinkse, Geisa Evaristo, Mervin Pieterse, Yuanjie Yu, Peter Verhaert
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:EuPA Open Proteomics
Subjects:
Amphibian skin secretion
Amidation
d-Amino acid
Tyrosine-sulfation
Pyroglutamic acid
Disulfide bridges
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968514000671

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http://www.sciencedirect.com/science/article/pii/S2212968514000671

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