Rethinking the cilia hypothesis of hydrocephalus

Dysfunction of motile cilia in ependymal cells has been proposed to be a pathogenic cause of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in hydrocephalus, primarily based on observations of enlarged ventricles in mouse models of primary ciliary dyskinesia. Here, we re...

Full description

Bibliographic Details
Main Authors: Phan Q. Duy, Ana B.W. Greenberg, William E. Butler, Kristopher T. Kahle
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122003059