MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production.

MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production.

Mannan-binding lectin (MBL), a lectin homologous to C1q, greatly facilitates C3/C4-mediated opsonophagocytosis of Candida albicans (C. albicans) by human neutrophils, and has the capacity to bind to CR1 (CD35) expressed on circulating neutrophils. The intracellular pool of neutrophil Dectin-1 plays...

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Bibliographic Details
Main Authors: Dongsheng Li, Bilin Dong, Zhongsheng Tong, Qinning Wang, Weihuang Liu, Yan Wang, Wei Liu, Jinbo Chen, Li Xu, Liuqing Chen, Yiqun Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519760?pdf=render

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http://europepmc.org/articles/PMC3519760?pdf=render

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