MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production.
Mannan-binding lectin (MBL), a lectin homologous to C1q, greatly facilitates C3/C4-mediated opsonophagocytosis of Candida albicans (C. albicans) by human neutrophils, and has the capacity to bind to CR1 (CD35) expressed on circulating neutrophils. The intracellular pool of neutrophil Dectin-1 plays...
Main Authors: | Dongsheng Li, Bilin Dong, Zhongsheng Tong, Qinning Wang, Weihuang Liu, Yan Wang, Wei Liu, Jinbo Chen, Li Xu, Liuqing Chen, Yiqun Duan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3519760?pdf=render |
Similar Items
-
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
by: Bilin Dong, et al.
Published: (2014-01-01) -
Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2.
by: Sheng-Yang Wu, et al.
Published: (2019-11-01) -
Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.
by: Mohlopheni J Marakalala, et al.
Published: (2013-01-01) -
Association of human antibodies to arabinomannan with enhanced mycobacterial opsonophagocytosis and intracellular growth reduction
by: McShane, H, et al.
Published: (2016) -
Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans
by: Hui Shen, et al.
Published: (2020-07-01)