A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.

A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.

Lyme disease (LD) caused by Borrelia burgdorferi is among the most important human vector borne diseases for which there is no effective prevention method. Identification of tick saliva transmission factors of the LD agent is needed before the highly advocated tick antigen-based vaccine could be dev...

Full description

Bibliographic Details
Main Authors: Thu-Thuy Nguyen, Tae Heung Kim, Emily Bencosme-Cuevas, Jacquie Berry, Alex Samuel Kiarie Gaithuma, Moiz Ashraf Ansari, Tae Kwon Kim, Lucas Tirloni, Zeljko Radulovic, James J Moresco, John R Yates, Albert Mulenga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012032&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012032&type=printable

Similar Items