Downregulation of ATM and BRCA1 Predicts Poor Outcome in Head and Neck Cancer: Implications for ATM-Targeted Therapy

Downregulation of ATM and BRCA1 Predicts Poor Outcome in Head and Neck Cancer: Implications for ATM-Targeted Therapy

<i>ATM</i> and <i>BRCA1</i> are DNA repair genes that play a central role in homologous recombination repair. Alterations of <i>ATM</i> and <i>BRCA1</i> gene expression are found in cancers, some of which are correlated with treatment response and pati...

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Bibliographic Details
Main Authors: Yu-Chu Wang, Ka-Wo Lee, Yi-Shan Tsai, Hsing-Han Lu, Si-Yun Chen, Hsin-Ying Hsieh, Chang-Shen Lin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Personalized Medicine
Subjects:
<i>ATM</i>
<i>BRCA1</i>
biomarker
betel quid
head and neck cancer
KU55933
Online Access:https://www.mdpi.com/2075-4426/11/5/389

Internet

https://www.mdpi.com/2075-4426/11/5/389

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