Augmented inhibition of angiogenesis by combination of HER2 antibody chA21 and trastuzumab in human ovarian carcinoma xenograft

<p>Abstract</p> <p>Background</p> <p>chA21 is a novel tumor-inhibitory antibody which recognized subdomain I of HER2 extracellular domain with an epitope distinct from other HER2 antibodies. Previously, we demonstrated that chA21 inhibits human ovarian carcinoma cell li...

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Bibliographic Details
Main Authors: Zhang Anli, Shen Guodong, Zhao Ting, Zhang Guihong, Liu Jing, Song Lihua, Wei Wei, Bing Ling, Wu Zhengsheng, Wu Qiang
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Journal of Ovarian Research
Online Access:http://www.ovarianresearch.com/content/3/1/20