5-Methoxytryptophan Sensitizing Head and Neck Squamous Carcinoma Cell to Cisplatitn Through Inhibiting Signal Transducer and Activator of Transcription 3 (STAT3)

5-Methoxytryptophan Sensitizing Head and Neck Squamous Carcinoma Cell to Cisplatitn Through Inhibiting Signal Transducer and Activator of Transcription 3 (STAT3)

Head and neck squamous cell carcinoma (HNSCC) is a common cancer of the oral cavity. Cisplatin (CDDP) is the ideal chemo-radiotherapy used for several tumor types, but resistance to the drug has become a major obstacle in treating patients with HNSCC. 5-methoxytryptophan (5-MTP), a 5-methoxyindole m...

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Bibliographic Details
Main Authors: Yu-Chieh Su, Chih-Chun Wang, Jui-Hsi Weng, Shyh-An Yeh, Po-Jen Chen, Tzer-Zen Hwang, Huang-Chi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
head and neck squamous cell carcinoma
cisplatin
5-methoxytryptophan
STAT3
4NQO
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.834941/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.834941/full

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