Computer-aided comprehensive explorations of RNA structural polymorphism through complementary simulation methods

While RNA folding was originally seen as a simple problem to solve, it has been shown that the promiscuous interactions of the nucleobases result in structural polymorphism, with several competing structures generally observed for non-coding RNA. This inherent complexity limits our understanding of...

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Bibliographic Details
Main Authors: Konstantin Röder, Guillaume Stirnemann, Pietro Faccioli, Samuela Pasquali
Format: Article
Language:English
Published: Cambridge University Press 2022-01-01
Series:QRB Discovery
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2633289222000199/type/journal_article