A Novel Molecular Diagnostic of Glioblastomas: Detection of an Extracellular Fragment of Protein Tyrosine Phosphatase μ

A Novel Molecular Diagnostic of Glioblastomas: Detection of an Extracellular Fragment of Protein Tyrosine Phosphatase μ

We recently found that normal human brain and low-grade astrocytomas express the receptor protein tyrosine phosphatase mu (PTPμ) and that the more invasive astrocytomas, glioblastoma multiforme (GBM), downregulate full-length PTPμ expression. Loss of PTPμ expression in GBMs is due to proteolytic cle...

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Bibliographic Details
Main Authors: Susan M. Burden-Gulley, Theresa J. Gates, Adam M. Burgoyne, Jennifer L. Cutter, David T. Lodowski, Shenandoah Robinson, Andrew E. Sloan, Robert H. Miller, James P. Basilion, Susann M. Brady-Kalnay
Format: Article
Language:English
Published: Elsevier 2010-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800090

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http://www.sciencedirect.com/science/article/pii/S1476558610800090

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