Landscape of germline pathogenic variants in patients with dual primary breast and lung cancer

Landscape of germline pathogenic variants in patients with dual primary breast and lung cancer

Abstract Background Cancer predisposition is most often studied in the context of single cancers. However, inherited cancer predispositions can also give rise to multiple primary cancers. Yet, there is a paucity of studies on genetic predisposition in multiple primary cancers, especially those outsi...

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Bibliographic Details
Main Authors: Ning-Yuan Lee, Melissa Hum, Sabna Zihara, Lanying Wang, Matthew K. Myint, Darren Wan-Teck Lim, Chee-Keong Toh, Anders Skanderup, Jens Samol, Min-Han Tan, Peter Ang, Soo-Chin Lee, Eng-Huat Tan, Gillianne G. Y. Lai, Daniel S. W. Tan, Yoon-Sim Yap, Ann S. G. Lee
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Human Genomics
Subjects:
Multiple primary cancers
Breast cancer
Lung cancer
Whole-exome sequencing
Germline variants
Online Access:https://doi.org/10.1186/s40246-023-00510-7

Internet

https://doi.org/10.1186/s40246-023-00510-7

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