Characterization of gut microbiota dynamics in an Alzheimer’s disease mouse model through clade-specific marker-based analysis of shotgun metagenomic data

Characterization of gut microbiota dynamics in an Alzheimer’s disease mouse model through clade-specific marker-based analysis of shotgun metagenomic data

Abstract Alzheimer’s disease (AD) is a complex neurodegenerative disorder significantly impairing cognitive faculties, memory, and physical abilities. To characterize the modulation of the gut microbiota in an in vivo AD model, we performed shotgun metagenomics sequencing on 3xTgAD mice at key time...

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Bibliographic Details
Main Authors: Francesco Favero, Angela Re, Mohammed Salim Dason, Teresa Gravina, Mara Gagliardi, Marta Mellai, Marco Corazzari, Davide Corà
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Biology Direct
Subjects:
Shotgun metagenomics
Alzheimer’s disease
3xTgAD mice
Gut microbiota
MetaPhlAn 4
Online Access:https://doi.org/10.1186/s13062-024-00541-7

Internet

https://doi.org/10.1186/s13062-024-00541-7

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