A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonatesResearch in context

A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonatesResearch in context

Summary: Background: Worldwide, Escherichia coli is the leading cause of neonatal Gram-negative bacterial meningitis, but full understanding of the pathogenesis of this disease is not yet achieved. Moreover, to date, no vaccine is available against bacterial neonatal meningitis. Methods: Here, we u...

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Bibliographic Details
Main Authors: Stéphanie Pons, Eric Frapy, Youssouf Sereme, Charlotte Gaultier, François Lebreton, Andrea Kropec, Olga Danilchanka, Laura Schlemmer, Cécile Schrimpf, Margaux Allain, François Angoulvant, Hervé Lecuyer, Stéphane Bonacorsi, Hugues Aschard, Harry Sokol, Colette Cywes-Bentley, John J. Mekalanos, Thomas Guillard, Gerald B. Pier, Damien Roux, David Skurnik
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:EBioMedicine
Subjects:
Neonatal meningitis
Vaccine
High-throughput sequencing
E. coli K1
PNAG
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642300004X

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http://www.sciencedirect.com/science/article/pii/S235239642300004X

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