COVID-19 Vaccine Booster Shot Preserves T Cells Immune Response Based on Interferon-Gamma Release Assay in Inflammatory Bowel Disease (IBD) Patients on Anti-TNFα Treatment

COVID-19 Vaccine Booster Shot Preserves T Cells Immune Response Based on Interferon-Gamma Release Assay in Inflammatory Bowel Disease (IBD) Patients on Anti-TNFα Treatment

Immune-modifying treatment in inflammatory bowel disease (IBD) impairs the humoral response. The role of T lymphocytes in this setting is still unclear. This study aims to assess if a booster shot (third dose) of BNT162b2 mRNA COVID-19 vaccine enhanced the humoral response and elicited cellular immu...

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Bibliographic Details
Main Authors: Grazia Pavia, Rocco Spagnuolo, Angela Quirino, Nadia Marascio, Aida Giancotti, Silvio Simeone, Cristina Cosco, Elena Tino, Federico Carrabetta, Gianfranco Di Gennaro, Carmelo Nobile, Aida Bianco, Giovanni Matera, Patrizia Doldo
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
cellular immune response
humoral immune response
anti-SARS-CoV-2 immunogenicity
inflammatory bowel disease
anti-TNFα agents
Online Access:https://www.mdpi.com/2076-393X/11/3/591

Internet

https://www.mdpi.com/2076-393X/11/3/591

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