Serum opacity factor rescues fertility among female Scarb1−/− mice by reducing HDL-free cholesterol bioavailability

Human female infertility, 20% of which is idiopathic, is a public health problem for which better diagnostics and therapeutics are needed. A novel cause of infertility emerged from studies of female mice deficient in the HDL receptor gene (Scarb1). These mice are infertile and have high plasma HDL c...

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Bibliographic Details
Main Authors: Corina Rosales, Dedipya Yelamanchili, Baiba K. Gillard, Jing Liu, Antonio M. Gotto, Jr., Henry J. Pownall
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001602