Projecting RNA measurements onto single cell atlases to extract cell type-specific expression profiles using scProjection

Abstract Multi-modal single cell RNA assays capture RNA content as well as other data modalities, such as spatial cell position or the electrophysiological properties of cells. Compared to dedicated scRNA-seq assays however, they may unintentionally capture RNA from multiple adjacent cells, exhibit...

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Bibliographic Details
Main Authors: Nelson Johansen, Hongru Hu, Gerald Quon
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40744-6