Clopidogrel inhibits angiogenesis of gastric ulcer healing via downregulation of vascular endothelial growth factor receptor 2

Although clopidogrel does not cause gastric mucosal injury, it does not prevent peptic ulcer recurrence in high-risk patients. We explored whether clopidogrel delays gastric ulcer healing via inhibiting angiogenesis and to elucidate the possible mechanisms. Methods: Gastric ulcers were induced in Sp...

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Bibliographic Details
Main Authors: Jiing-Chyuan Luo, Yen-Ling Peng, Tseng-Shing Chen, Teh-Ia Huo, Ming-Chih Hou, Hui-Chun Huang, Han-Chieh Lin, Fa-Yauh Lee
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664615002788