Identifying and Exploring the Candidate Susceptibility Genes of Cirrhosis Using the Multi-Tissue Transcriptome-Wide Association Study

Identifying and Exploring the Candidate Susceptibility Genes of Cirrhosis Using the Multi-Tissue Transcriptome-Wide Association Study

Objective: We identify and explore the candidate susceptibility genes for cirrhosis and their underlying biological mechanism.Methods: We downloaded the genome-wide association studies summary data of 901 cirrhosis cases and 451,363 controls and integrated them with reference models of five potentia...

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Bibliographic Details
Main Authors: Xiao-Bo Zhu, Yu-Qing Hou, Xiang-Yu Ye, Yi-Xin Zou, Xue-Shan Xia, Sheng Yang, Peng Huang, Rong-Bin Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
transcriptome-wide association study
cirrhosis
multiple tissues
genome-wide association studies
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.878607/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.878607/full

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