The Use of Real-Time Quaking-Induced Conversion for the Diagnosis of Human Prion Diseases

Prion diseases are rapidly progressive, invariably fatal, transmissible neurodegenerative disorders associated with the accumulation of the amyloidogenic form of the prion protein in the central nervous system (CNS). In humans, prion diseases are highly heterogeneous both clinically and neuropatholo...

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Bibliographic Details
Main Authors: Anna Poleggi, Simone Baiardi, Anna Ladogana, Piero Parchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.874734/full