ERVK13-1/miR-873-5p/GNMT Axis Promotes Metastatic Potential in Human Bladder Cancer though Sarcosine Production

ERVK13-1/miR-873-5p/GNMT Axis Promotes Metastatic Potential in Human Bladder Cancer though Sarcosine Production

N-methyl-glycine (sarcosine) is known to promote metastatic potential in some cancers; however, its effects on bladder cancer are unclear. T24 cells derived from invasive cancer highly expressed GNMT, and S-adenosyl methionine (SAM) treatment increased sarcosine production, promoting proliferation,...

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Bibliographic Details
Main Authors: Shingo Kishi, Shiori Mori, Rina Fujiwara-Tani, Ruiko Ogata, Rika Sasaki, Ayaka Ikemoto, Kei Goto, Takamitsu Sasaki, Makito Miyake, Satoru Sasagawa, Masashi Kawaichi, Yi Luo, Ujjal Kumar Bhawal, Kiyohide Fujimoto, Hidemitsu Nakagawa, Hiroki Kuniyasu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
SAM
GNMT
sarcosine
cancer metastasis
bladder cancer
Online Access:https://www.mdpi.com/1422-0067/24/22/16367

Internet

https://www.mdpi.com/1422-0067/24/22/16367

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