p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic Significances

p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic Significances

<i>CDKN2A</i> is a tumor suppressor gene encoding the p16 protein, a key regulator of the cell cycle. <i>CDKN2A</i> homozygous deletion is a central prognostic factor for numerous tumors and can be detected by several techniques. This study aims to evaluate the extent to whic...

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Bibliographic Details
Main Authors: Lucas Geyer, Thibaut Wolf, Marie-Pierre Chenard, Helene Cebula, Roland Schott, Georges Noel, Eric Guerin, Erwan Pencreach, Damien Reita, Natacha Entz-Werlé, Benoît Lhermitte
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
p16
immunohistochemistry
<i>CDKN2A</i> deletion
FISH
gliomas
prognosis
Online Access:https://www.mdpi.com/2072-6694/15/5/1512

Internet

https://www.mdpi.com/2072-6694/15/5/1512

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