The immunoproteasome‐specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis

The immunoproteasome‐specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis

Abstract Severe heart pathology upon virus infection is closely associated with the immunological equipment of the host. Since there is no specific treatment available, current research focuses on identifying new drug targets to positively modulate predisposing immune factors. Utilizing a murine mod...

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Bibliographic Details
Main Authors: Nadine Althof, Carl Christoph Goetzke, Meike Kespohl, Karolin Voss, Arnd Heuser, Sandra Pinkert, Ziya Kaya, Karin Klingel, Antje Beling
Format: Article
Language:English
Published: Springer Nature 2018-01-01
Series:EMBO Molecular Medicine
Subjects:
immunology and inflammation
infectious diseases
myocarditis
proteasome
virus
Online Access:https://doi.org/10.15252/emmm.201708089

Internet

https://doi.org/10.15252/emmm.201708089

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