Prevalence of the <it>BRCA1 </it>founder mutation c.5266dupin Brazilian individuals at-risk for the hereditary breast and ovarian cancer syndrome

Prevalence of the <it>BRCA1 </it>founder mutation c.5266dupin Brazilian individuals at-risk for the hereditary breast and ovarian cancer syndrome

<p>Abstract</p> <p>About 5-10% of breast and ovarian carcinomas are hereditary and most of these result from germline mutations in the <it>BRCA1 </it>and <it>BRCA2 </it>genes. In women of Ashkenazi Jewish ascendance, up to 30% of breast and ovarian carcinoma...

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Bibliographic Details
Main Authors: Ewald Ingrid P, Izetti Patrícia, Vargas Fernando R, Moreira Miguel AM, Moreira Aline S, Moreira-Filho Carlos A, Cunha Danielle R, Hamaguchi Sara, Camey Suzi A, Schmidt Aishameriane, Caleffi Maira, Koehler-Santos Patrícia, Giugliani Roberto, Ashton-Prolla Patricia
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Hereditary breast cancer
Hereditary breast and ovarian cancer Syndrome
Founder mutations
<it>BRCA1 </it>gene
<it>BRCA2 </it>gene
Online Access:http://www.hccpjournal.com/content/9/1/12

Internet

http://www.hccpjournal.com/content/9/1/12

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