Autophagy, a novel pathway to regulate calcium mobilization in T lymphocytes

Autophagy, a novel pathway to regulate calcium mobilization in T lymphocytes

The T lymphocyte response initiates with the recognition of MHC/peptides on antigen presenting cells by the T cell receptor (TCR). After the TCR engagement, the proximal signaling pathways are activated for downstream cellular events. Among these pathways, the calcium signaling flux is activated thr...

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Bibliographic Details
Main Authors: Wei eJia, Mingxiao eHe, You-Wen eHe, Ian eMcleod
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Autophagy
T lymphocytes
Calcium flux
ER homeostasis
ER-phagy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00179/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00179/full

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