Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular CarcinomaSummary

Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular CarcinomaSummary

Background & Aims: Hepatocellular carcinoma (HCC) is a highly heterogeneous solid tumor with high morbidity and mortality. AT-rich interaction domain 1A (ARID1A) accounts for up to 10% of mutations in liver cancer, however, its role in HCC remains controversial, and no targeted therapy has b...

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Bibliographic Details
Main Authors: Feng-Kun Zhang, Qian-Zhi Ni, Kang Wang, Hui-Jun Cao, Dong-Xian Guan, Er-Bin Zhang, Ning Ma, Yi-Kang Wang, Qian-Wen Zheng, Sheng Xu, Bing Zhu, Tian-Wei Chen, Ji Xia, Xiao-Song Qiu, Xu-Fen Ding, Hao Jiang, Lin Qiu, Xiang Wang, Wei Chen, Shu-Qun Cheng, Dong Xie, Jing-Jing Li
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
SWI/SNF Complex
HDAC1
Epigenetic
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22000613

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http://www.sciencedirect.com/science/article/pii/S2352345X22000613

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