Impact of Helicobacter pylori biofilm formation on clarithromycin susceptibility and generation of resistance mutations.

The human gastric pathogen Helicobacter pylori forms biofilms in vitro and in vivo. The purpose of this study was to evaluate the effects of H. pylori biofilm formation in vitro on clarithromycin (CLR) susceptibility. CLR susceptibility of H. pylori intermediate (2-day) and mature (3-day) biofilms o...

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Bibliographic Details
Main Authors: Hideo Yonezawa, Takako Osaki, Tomoko Hanawa, Satoshi Kurata, Kuniyasu Ochiai, Shigeru Kamiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765302?pdf=render