IGF2BP2 Induces U251 Glioblastoma Cell Chemoresistance by Inhibiting FOXO1-Mediated PID1 Expression Through Stabilizing lncRNA DANCR

IGF2BP2 Induces U251 Glioblastoma Cell Chemoresistance by Inhibiting FOXO1-Mediated PID1 Expression Through Stabilizing lncRNA DANCR

Glioma is the most common type of malignant tumor of the nervous system and is characterized by high mortality and poor outcome. This study aims to investigate the mechanism underlying IGF2 mRNA-binding protein 2 (IGF2BP2) and long noncoding RNA DANCR in etoposide resistance of glioblastoma (GBM) ce...

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Bibliographic Details
Main Authors: Junfei Han, Xiaojun Yu, Shanxi Wang, Yingguang Wang, Qikun Liu, Haoran Xu, Xiaosong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
glioma
drug resistance
glioblastoma
IGF2BP2
DANCR
FoxO1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.659228/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.659228/full

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