Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation

Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation

The use of cyclodextrins as drug nano-carrier systems for drug delivery is gaining importance in the pharmaceutical industry due to the interesting pharmacokinetic properties of the resulting inclusion complexes. In the present work, complexes of the anti-cancer alkaloids camptothecin and luotonin A...

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Bibliographic Details
Main Authors: Víctor González-Ruiz, Ángel Cores, Olmo Martín-Cámara, Karen Orellana, Víctor Cervera-Carrascón, Patrycja Michalska, Ana I. Olives, Rafael León, M. Antonia Martín, J. Carlos Menéndez
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
molecular recognition
cavitands
supramolecular complexes
anticancer agents
drug stabilization
Online Access:https://www.mdpi.com/1999-4923/13/10/1609

Internet

https://www.mdpi.com/1999-4923/13/10/1609

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