Role of PARP and TRPM2 in VEGF Inhibitor‐Induced Vascular Dysfunction

Background Hypertension and vascular toxicity are major unwanted side effects of antiangiogenic drugs, such as vascular endothelial growth factor inhibitors (VEGFis), which are effective anticancer drugs but have unwanted side effects, including vascular toxicity and hypertension. Poly (ADP‐ribose)...

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Bibliographic Details
Main Authors: Karla B. Neves, Rheure Alves‐Lopes, Augusto C. Montezano, Rhian M. Touyz
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.027769