PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adultsResearch in context

PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adultsResearch in context

Summary: Background: PfSPZ Vaccine, a promising pre-erythrocytic stage malaria vaccine candidate based on whole, radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), has proven safe and effective in mediating sterile protection from malaria in malaria-naïve and exposed healthy adults....

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Main Authors: Anneth Tumbo, Freia-Raphaella Lorenz, Annie S.P. Yang, Stephanie Sefried, Tobias Schindler, Maximilian Mpina, Jean-Pierre Dangy, Florence A. Milando, Mohammed A. Rashid, Gloria Nyaulingo, Kamaka Ramadhani, Said Jongo, Philip L. Felgner, Yonas Abebe, B. Kim Lee Sim, L.W. Preston Church, Thomas L. Richie, Peter F. Billingsley, Tooba Murshedkar, Stephen L. Hoffman, Salim Abdulla, Peter G. Kremsner, Benjamin Mordmüller, Claudia Daubenberger, Rolf Fendel
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:EBioMedicine
Subjects:
HIV
PfSPZ Vaccine
Plasmodium falciparum
Plasmodium falciparum circumsporozoite protein
Plasmodium falciparum merozoite surface protein 5
Protein microarray
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004006

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http://www.sciencedirect.com/science/article/pii/S2352396424004006

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