Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response

Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response

Hepatitis delta virus (HDV), a satellite virus of HBV, is regarded as the most severe type of hepatitis virus because of the substantial morbidity and mortality. The IFN system is the first line of defense against viral infections and an essential element of antiviral immunity; however, the role of...

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Bibliographic Details
Main Authors: Takeshi Chida, Yuji Ishida, Sho Morioka, Go Sugahara, Christine Han, Bill Lam, Chihiro Yamasaki, Remi Sugahara, Meng Li, Yasuhito Tanaka, T. Jake Liang, Chise Tateno, Takeshi Saito
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-05-01
Series:JCI Insight
Subjects:
Hepatology
Virology
Online Access:https://doi.org/10.1172/jci.insight.162404

Internet

https://doi.org/10.1172/jci.insight.162404

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