An opposing function of paralogs in balancing developmental synapse maturation.

The disc-large (DLG)-membrane-associated guanylate kinase (MAGUK) family of proteins forms a central signaling hub of the glutamate receptor complex. Among this family, some proteins regulate developmental maturation of glutamatergic synapses, a process vulnerable to aberrations, which may lead to n...

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Bibliographic Details
Main Authors: Plinio D Favaro, Xiaojie Huang, Leon Hosang, Sophia Stodieck, Lei Cui, Yu-Zhang Liu, Karl-Alexander Engelhardt, Frank Schmitz, Yan Dong, Siegrid Löwel, Oliver M Schlüter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006838