Vitamin D3 suppresses intestinal epithelial stemness via ER stress induction in intestinal organoids

Vitamin D3 suppresses intestinal epithelial stemness via ER stress induction in intestinal organoids

Abstract Background Vitamin D3 is important for normal function of the intestinal epithelial cells (IECs). In this study, we aimed to investigate the effects of vitamin D3 on the differentiation, stemness, and viability of healthy IECs in intestinal organoids. Methods Intestinal organoids derived fr...

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Bibliographic Details
Main Authors: Panida Sittipo, Hyun Kyu Kim, Jaeseok Han, Man Ryul Lee, Yun Kyung Lee
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Intestinal epithelial cells (IECs)
Intestinal organoids
Vitamin D3
Endoplasmic reticulum (ER) stress
Online Access:https://doi.org/10.1186/s13287-021-02361-2

Internet

https://doi.org/10.1186/s13287-021-02361-2

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