1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2. Here, we established a method to screen inhibitors of N protein by using microscale thermophoresis assays to obtain potentia...

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Bibliographic Details
Main Authors: Yang Liu, Kuiru Sa, Wei Xu, Yongkang Chen, Jing Liang, Peng Zou, Lixia Chen
Format: Article
Language:English
Published: Compuscript Ltd 2023-07-01
Series:Acta Materia Medica
Subjects:
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0021