Tailoring hyaluronic acid hydrogels: Impact of cross-linker length and density on skin rejuvenation as injectable dermal fillers and their potential effects on the MAPK signaling pathway suppression

Tailoring hyaluronic acid hydrogels: Impact of cross-linker length and density on skin rejuvenation as injectable dermal fillers and their potential effects on the MAPK signaling pathway suppression

Hyaluronic acid (HA) hydrogels, obtained through cross-linking, provide a stable 3D environment that is important for controlled delivery and tissue engineering applications. Cross-linking density has a significant impact on the physicochemical properties of hydrogels, including their shape stabilit...

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Bibliographic Details
Main Authors: Mohanapriya Murugesan, Ramya Mathiyalagan, Zelika Mega Ramadhania, Jinnatun Nahar, Cuong Hung Luu, V.H. Giang Phan, Deok Chun Yang, Qihui Zhou, Se Chan Kang, Thavasyappan Thambi
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-07-01
Series:Bioactive Materials
Subjects:
Hyaluronic acid
Cross-linking
Injectability
Dermal filler
Anti-wrinkling
MAPK signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001045

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X25001045

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