Pericardial irradiation dose may be strongly associated with grade 4 lymphopenia and affect prognosis in patients with locally advanced esophageal cancer receiving definitive concurrent chemoradiotherapy

Pericardial irradiation dose may be strongly associated with grade 4 lymphopenia and affect prognosis in patients with locally advanced esophageal cancer receiving definitive concurrent chemoradiotherapy

Abstract Background The immune system may influence prognosis, and lymphopenia is a frequent side effect of concurrent chemoradiotherapy (CCRT). Radical irradiation for locally advanced esophageal cancer (LA‐EC) exposes significant vascular and heart volumes. In this study, we hypothesized that lymp...

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Bibliographic Details
Main Authors: Xianyan Chen, Xiaoman Tian, Xuanwei Zhang, Qianyue Deng, Min Wang, Xiaojuan Zhou, Yong Xu, Lin Zhou, Bingwen Zou, Yongmei Liu, Rui Ao, You Lu, Youling Gong
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Thoracic Cancer
Subjects:
concurrent chemoradiotherapy
immune‐checkpoint inhibitor
locally advanced esophageal cancer
lymphopenia
pericardial irradiation
Online Access:https://doi.org/10.1111/1759-7714.15057

Internet

https://doi.org/10.1111/1759-7714.15057

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