The Bacteroidetes Q-rule and glutaminyl cyclase activity increase the stability of extracytoplasmic proteins

The Bacteroidetes Q-rule and glutaminyl cyclase activity increase the stability of extracytoplasmic proteins

ABSTRACT In Gram-negative didermal species of the phylum Bacteroidetes, the majority of pre(pro)proteins exported across the cell membrane via the Sec system follow the Q-rule: a glutamine residue immediately downstream of a leader peptide is exposed as the new amino terminus by type I signal peptid...

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Bibliographic Details
Main Authors: Katarzyna Szczęśniak, Florian Veillard, Carsten Scavenius, Kamila Chudzik, Kinga Ferenc, Matthias Bochtler, Jan Potempa, Danuta Mizgalska
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
posttranslational modification
pyroglutamyl formation
proteolysis
Porphyromonas gingivalis
essential protein
periodontitis
Online Access:https://journals.asm.org/doi/10.1128/mbio.00980-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00980-23

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