Refractory cold agglutinin disease successfully treated with daratumumab. A case report and review of literature

Refractory cold agglutinin disease successfully treated with daratumumab. A case report and review of literature

ABSTRACTBackground: Cold agglutinin disease (CAD) is immune-mediated hemolytic anemia. The disease is caused by cold reactive autoantibodies that induce hemolysis through the activation of the complement pathway. Most patients with CAD are elderly, and half may have refractory CAD that may not respo...

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Bibliographic Details
Main Authors: Abdelaziz Mohamed, Mohammed Alkhatib, Awni Alshurafa, Halima El Omri
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Hematology
Subjects:
Cold agglutinin disease
hemolytic anemia
daratumumab
autoimmune diseases
monoclonal antibodies
hemoglobin
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2023.2252651

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https://www.tandfonline.com/doi/10.1080/16078454.2023.2252651

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