Conserved NIMA kinases regulate multiple steps of endocytic trafficking.

Human NIMA-related kinases have primarily been studied for their roles in cell cycle progression (NEK1/2/6/7/9), checkpoint-DNA-damage control (NEK1/2/4/5/10/11), and ciliogenesis (NEK1/4/8). We previously showed that Caenorhabditis elegans NEKL-2 (NEK8/9 homolog) and NEKL-3 (NEK6/7 homolog) regulat...

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Bibliographic Details
Main Authors: Braveen B Joseph, Naava Naslavsky, Shaonil Binti, Sylvia Conquest, Lexi Robison, Ge Bai, Rafael O Homer, Barth D Grant, Steve Caplan, David S Fay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010741