HCLC-FC: A novel statistical method for phenome-wide association studies.

The emergence of genetic data coupled to longitudinal electronic medical records (EMRs) offers the possibility of phenome-wide association studies (PheWAS). In PheWAS, the whole phenome can be divided into numerous phenotypic categories according to the genetic architecture across phenotypes. Curren...

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Bibliographic Details
Main Authors: Xiaoyu Liang, Xuewei Cao, Qiuying Sha, Shuanglin Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0276646