Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome.

Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal alleles can stay at high or moderate frequency within a population, especially if recessive lethal alleles exhibit an advantage for favourable t...

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Bibliographic Details
Main Authors: Martijn F L Derks, Marcos S Lopes, Mirte Bosse, Ole Madsen, Bert Dibbits, Barbara Harlizius, Martien A M Groenen, Hendrik-Jan Megens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6166978?pdf=render