Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection

Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent studies demonstrated that host cholesterol levels have implications in the establishment of Mycobacterium tuberculosis (M. tub...

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Bibliographic Details
Main Authors: Jinrui Xu, Yanbing Zhou, Yi Yang, Cuiping Lv, Xiaoming Liu, Yujiong Wang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12865-020-00356-x