Macrophages and Epithelial Cells Mutually Interact through NLRP3 to Clear Infection and Enhance the Gastrointestinal Barrier

Activation of the nod-like receptor protein 3 (NLRP3) leads to the release of the proinflammatory cytokine IL-1β, which then facilitates pathogen control by macrophages. The role of NLRPs in controlling infection of epithelial cells is not well understood. Our hypothesis was that activation of the N...

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Bibliographic Details
Main Authors: Michael Bording-Jorgensen, Heather Armstrong, Madison Wickenberg, Paul LaPointe, Eytan Wine
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Immuno
Subjects:
Online Access:https://www.mdpi.com/2673-5601/2/1/2