Macrophages and Epithelial Cells Mutually Interact through NLRP3 to Clear Infection and Enhance the Gastrointestinal Barrier
Activation of the nod-like receptor protein 3 (NLRP3) leads to the release of the proinflammatory cytokine IL-1β, which then facilitates pathogen control by macrophages. The role of NLRPs in controlling infection of epithelial cells is not well understood. Our hypothesis was that activation of the N...
Main Authors: | Michael Bording-Jorgensen, Heather Armstrong, Madison Wickenberg, Paul LaPointe, Eytan Wine |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
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Series: | Immuno |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-5601/2/1/2 |
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