Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies

Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies

Abstract Background Expression of SRY [sex-determining region Y]-box11 (SOX11) is specific to mantle cell lymphoma (MCL) and contributes, in conjunction with immunoglobulin variable heavy chain gene mutation status, to the identification of two forms of this disease. Methods The aim of this report w...

Full description

Bibliographic Details
Main Authors: Julien Magne, Alizée Jenvrin, Adrien Chauchet, Olivier Casasnovas, Anne Donzel, Laurence Jego, Bernard Aral, Julien Guy, Nathalie Nadal, Dewi Vernerey, Patrick Callier, Francine Garnache-Ottou, Christophe Ferrand
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Experimental Hematology & Oncology
Subjects:
Mantle cell lymphoma
SOX11
RT-qPCR-reference genes
ROC curve analysis-threshold
Online Access:http://link.springer.com/article/10.1186/s40164-018-0097-6

Internet

http://link.springer.com/article/10.1186/s40164-018-0097-6

Similar Items