Feedback circuits are numerous in embryonic gene regulatory networks and offer a stabilizing influence on evolution of those networks

Feedback circuits are numerous in embryonic gene regulatory networks and offer a stabilizing influence on evolution of those networks

Abstract The developmental gene regulatory networks (dGRNs) of two sea urchin species, Lytechinus variegatus (Lv) and Strongylocentrotus purpuratus (Sp), have remained remarkably similar despite about 50 million years since a common ancestor. Hundreds of parallel experimental perturbations of transc...

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Bibliographic Details
Main Authors: Abdull Jesus Massri, Brennan McDonald, Gregory A. Wray, David R. McClay
Format: Article
Language:English
Published: BMC 2023-06-01
Series:EvoDevo
Subjects:
Gene regulatory networks
Feedback circuits
Evolutionary mechanism
Embryonic specification
Sea urchin development
Online Access:https://doi.org/10.1186/s13227-023-00214-y

Internet

https://doi.org/10.1186/s13227-023-00214-y

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