Thrombotic microangiopathy in children: Redefining hemolytic uremic syndrome, thrombotic thrombocytopenic purpura and related disorders

Thrombotic microangiopathy in children: Redefining hemolytic uremic syndrome, thrombotic thrombocytopenic purpura and related disorders

Thrombotic microangiopathy (TMA) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and end-organ ischemic damage. The primary mechanism involved is the occurrence of microthrombi due to deficient activity of ADAMTS13 (A Disintegrin And Metalloprotease with ThromboSpondin type 1 repe...

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Bibliographic Details
Main Authors: Mamta Manglani, Pranoti Kini
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Pediatric Hematology Oncology Journal
Subjects:
Thrombotic microangiopathy (TMA)
Hemolytic uremic syndrome (HUS)
Thrombotic thrombocytopenia purpura (TTP)
ADAMTS13
Upshaw schulman syndrome (USS)
Online Access:http://www.sciencedirect.com/science/article/pii/S2468124524000056

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http://www.sciencedirect.com/science/article/pii/S2468124524000056

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