DNA Nanotechnology-Empowered Fluorescence Imaging of APE1 Activity

Apurinic/apyrimidinic endonuclease 1 (APE1), also known as redox factor-1 (Ref-1), is a multifunctional protein that exists widely in living organisms. It can specifically recognize and cleave the DNA in apurinic/apyrimidinic (AP) sites in the base excision repair (BER) pathway, as well as regulate...

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Bibliographic Details
Main Authors: Hui He, Xiaojun Liu, Yuchen Wu, Lanlin Qi, Jin Huang, Yan Zhou, Jiahao Zeng, Kemin Wang, Xiaoxiao He
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Chemistry
Subjects:
Online Access:https://www.mdpi.com/2624-8549/5/3/124