Dosage reduction of low weight heparin in patients with renal dysfunction: Effects on anti-Xa levels and clinical outcomes.

<h4>Background</h4>To prevent bio-accumulation of low molecular weight heparins (LMWHs) in patients with decreased kidney function, dosage reduction and anti-Xa monitoring has been suggested. The aim of this study was to investigate the effect of pre-emptive dosage reduction of LMWH on a...

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Main Authors: Paul Hornung, Meriem Khairoun, Friedo W Dekker, Karin A H Kaasjager, Albert Huisman, Lily Jakulj, Willem Jan W Bos, Frits R Rosendaal, Marianne C Verhaar, Gurbey Ocak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0239222